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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
22.73
Human Site:
S139
Identified Species:
38.46
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
S139
I
A
R
A
R
A
G
S
R
L
S
A
E
E
R
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
S142
A
R
A
G
S
R
L
S
V
S
F
A
E
E
R
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
S139
I
A
R
A
R
A
G
S
R
L
S
A
E
E
R
Dog
Lupus familis
XP_535342
274
31382
S139
I
A
R
A
R
A
G
S
R
L
S
A
E
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
S139
I
A
R
A
R
A
G
S
R
L
S
A
E
D
R
Rat
Rattus norvegicus
O70257
261
29832
K140
P
E
D
S
S
K
E
K
N
F
V
S
W
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
F130
R
E
E
Q
L
V
S
F
D
S
N
E
D
W
N
Chicken
Gallus gallus
XP_001232002
272
30779
S137
V
A
R
A
R
A
G
S
R
I
S
A
D
E
R
Frog
Xenopus laevis
NP_001079671
259
29246
S139
D
D
N
Q
K
E
G
S
L
L
T
W
E
N
E
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
V139
R
A
G
S
R
F
Q
V
D
E
L
N
Q
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
T163
L
E
I
T
G
R
P
T
N
D
D
E
L
E
K
Honey Bee
Apis mellifera
XP_396269
271
30684
A139
V
R
R
A
K
A
S
A
G
I
T
P
F
G
E
Nematode Worm
Caenorhab. elegans
O16000
291
33234
L154
K
G
R
I
Q
R
Q
L
D
I
A
G
K
Q
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
I144
T
P
V
V
T
K
E
I
P
T
S
Y
N
A
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
33.3
100
100
N.A.
93.3
6.6
N.A.
0
80
26.6
13.3
N.A.
6.6
20
6.6
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
20
N.A.
13.3
100
40
33.3
N.A.
26.6
53.3
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
8
43
0
43
0
8
0
0
8
43
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
0
0
0
0
22
8
8
0
15
15
0
% D
% Glu:
0
22
8
0
0
8
15
0
0
8
0
15
43
50
22
% E
% Phe:
0
0
0
0
0
8
0
8
0
8
8
0
8
0
0
% F
% Gly:
0
8
8
8
8
0
43
0
8
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
29
0
8
8
0
0
0
8
0
22
0
0
0
0
0
% I
% Lys:
8
0
0
0
15
15
0
8
0
0
0
0
8
0
8
% K
% Leu:
8
0
0
0
8
0
8
8
8
36
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
15
0
8
8
8
8
8
% N
% Pro:
8
8
0
0
0
0
8
0
8
0
0
8
0
0
8
% P
% Gln:
0
0
0
15
8
0
15
0
0
0
0
0
8
8
0
% Q
% Arg:
15
15
50
0
43
22
0
0
36
0
0
0
0
0
43
% R
% Ser:
0
0
0
15
15
0
15
50
0
15
43
8
0
0
8
% S
% Thr:
8
0
0
8
8
0
0
8
0
8
15
0
0
0
0
% T
% Val:
15
0
8
8
0
8
0
8
8
0
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _